[Download] "Age- and Sex-Related Reference Values for Serum Adhesion Molecule Concentrations in Healthy Individuals: Intercellular Adhesion Molecule-1 and E-, P-, and L-Selectin (Technical Briefs)" by Clinical Chemistry * Book PDF Kindle ePub Free
eBook details
- Title: Age- and Sex-Related Reference Values for Serum Adhesion Molecule Concentrations in Healthy Individuals: Intercellular Adhesion Molecule-1 and E-, P-, and L-Selectin (Technical Briefs)
- Author : Clinical Chemistry
- Release Date : January 01, 2003
- Genre: Chemistry,Books,Science & Nature,
- Pages : * pages
- Size : 212 KB
Description
Intercellular adhesion molecule-1 (ICAM-1) and E-, P-, and L-selectin are cellular adhesion molecules involved in the recruitment of leukocytes on the activated vessel wall during inflammation (1) and play an important role in the early stages of atherosclerosis and its complications (2). Thus, the measurement of soluble adhesion molecules in serum may have diagnostic relevance in many inflammatory diseases (3). A profile of soluble adhesion molecule concentrations may allow better therapeutic decisions in inflammatory and autoimmune disorders, infection, cancer, and cardiovascular pathologies and may also aid in the prediction of cardiovascular events (4,5). However, the use of these markers in clinical practice depends critically on knowledge of their reference values. The purpose of the present study was to establish age-and sex-specific reference intervals for serum concentrations of soluble ICAM-1 and E-, P-, and L-selectin in healthy children (4-17 years) and adults (18-55 years).